Low IgG is not a disease in itself but a laboratory finding with two broad categories of causes:
begins with a quantitative serum immunoglobulin panel (IgG, IgA, IgM). Low total IgG must be confirmed with a repeat test. Crucially, a low number alone is insufficient; the functional response must be assessed via specific antibody response to vaccines (e.g., tetanus or pneumococcal polysaccharide vaccine). A failure to mount a protective antibody titer confirms a clinically significant deficiency. inmunoglobulina g baja
Immunoglobulin G (IgG) is the most abundant antibody isotype in human serum, constituting approximately 75-80% of all immunoglobulins. It serves as a cornerstone of the adaptive immune system, providing long-term defense against bacterial and viral pathogens. A low level of IgG, a condition known as hypogammaglobulinemia, represents a significant failure of humoral immunity. This essay explores the critical functions of IgG, the primary etiologies leading to its deficiency, the clinical consequences for affected patients, and the modern strategies for diagnosis and management. Low IgG is not a disease in itself