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Your brain cannot synthesize that noise. DAVID can.
If you’ve just finished an RNA-seq or microarray experiment, you probably have a list of genes. It might be a short list of 50 names or a long one of 2,000. But a list is just data. The real question is: What does this list mean biologically?
Here is your guide to getting the most out of DAVID functional annotation in 2024. Imagine you find 500 genes that are "turned on" during a heart attack. Reading each gene one by one is useless. You will see GAPDH (metabolism), IL6 (inflammation), TNNT2 (contraction), and CASP3 (apoptosis). david functional annotation
This is the most critical step users mess up. You must tell DAVID what the "universe" is. Are you looking at the whole human genome? Or just the 10,000 genes expressed in your specific tissue? Use the whole genome for standard enrichment, but use a tissue-specific background for precision.
Enter (The Database for Annotation, Visualization and Integrated Discovery). For nearly two decades, DAVID has been the Swiss Army knife of functional annotation. It answers the golden question of genomics: "Which biological processes are my genes involved in?" Your brain cannot synthesize that noise
This is where the magic happens. The Three Outputs You Must Understand When the results appear, you will see a wall of data. Ignore the noise and focus on these three things:
Go to [david.ncifcrf.gov] and turn your data into discovery. Have a favorite alternative (Enrichr, g:Profiler, Metascape)? Drop a comment below. But for my money, DAVID is still the gold standard for functional annotation. It might be a short list of 50 names or a long one of 2,000
But DAVID is
Monogatari is 100% open source and developed collaboratively by people from all over the world. Even if you're not a programmer, you can get involved and make a difference.
No matter what language you speak, you can help translating Monogatari's UI so that more people around the world can use it!
If you are a developer or simply have an idea for a new feature, you can become a code contributor and help developing Monogatari!
If you have found a bug, please report it so we can fix it. If you are a developer or simply want to contribute, you can also help fixing available bugs!
Have you found a missing piece of documentation or think you can improve it? Help everyone by writing documentation!
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Every little bit of support helps us continue developing new features, provide personalized support and maintain the project. There's lots of ways to sponsor the project!
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Monogatari would not be possible without these awesome and open source projects!
CSS library for entrance, exit and other animations
JavaScript library for DOM manipulation, storage and other utilities
CSS library for shake animations
Next-generation forum software used for the community forum.
Font used for all the icons on the UI
CSS library with all the base styling for grids, modals, etc.
JavaScript library for handling keyboard shortcuts
Web Components library for creation of custom elements
JavaScript library for creating particle systems
JavaScript library for creating typewriter text animations
Every story should be told before they are lost forever.
Monogatari's goal is not competition, here are some awesome Open Source engines you might want to check out!